In this paper, the design of a specific case study of a foyer space is concerned in healthcare facility. The design task of a healthcare facility in architectural perspective is one of the most challenging tasks in the architectural design field since it involves different spaces that have unique requirements. Specifically, a foyer space has been considered as a gathering area that answers people's needs and expectations. The study shows an application of computational intelligence for a skylight design in foyer space. For this reason, objective functions are considered to minimize skylight cost and to maximize the daylight performance of the interior space. Multi Objective Self Adaptive Ensemble Differential Evolution Algorithm and Non Dominated Sorting Genetic Algorithm II are proposed to tackle this complex problem. According to results, jEDEMO algorithm presents satisfactory solutions as well as NSGAII.