Roberto Santana Monte Igeldo

Roberto Santana

Intelligent System Group 
Department of Computer Science and Artificial Intelligence
University of the  Basque Country
Paseo Manuel de Lardizábal 1, 20080 San Sebastián - Donostia, Spain  

telefon + 34 943 01 8070     pdf Curriculum Vitae
email rsantana AT ehu.es


Research  Interests
  • Estimation of Distribution Algorithms
  • Probabilistic Graphical Models
  • Bioinformatics
  • Neurocomputing


Publications



2011

 
S. Shakya, R. Santana,  and  J. A. Lozano.  A Markovianity based Optimisation Algorithm. Genetic Programming and Evolvable Machines. Springer.  2011. Accepted for publication.

R. Santana,  C. Bielza,  and  P. Larrañaga.   Optimizing brain networks topologies using multi-objective evolutionary computation. Neuroinformatics. Vol. 9. No. 1. Pp. 3-19. 2011.

L. Lozada-Chang  and  R. Santana Univariate marginal distribution algorithm dynamics for a class of parametric functions with unitation constraints. Information Sciences.  Vol. 181. Pp. 2340-2355. 2011.

C. Echegoyen, A. Mendiburu, R. Santana, and J. A. Lozano. Towards understanding EDAs based on Bayesian networks through a quantitative analysis. IEEE Transactions on Evolutionary Computation. 2011. In Press.

R. Santana. Estimation of distribution algorithms: from available implementations to potential developments. In Companion Proceedings of the 2011 Genetic and Evolutionary Conference (GECCO-2011), Dublin, Ireland. ACM Digital Library. Pp. 679-686.  2011. 

R. Santana,  S. Muelas, A. LaTorre, J. M. Peña. A Direct Optimization Approach to the P300 Speller. In Proceedings of the 2011 Genetic and Evolutionary Conference (GECCO-2011), Dublin, Ireland. ACM Digital Library.  Pp. 1747-1754. 2011.    

R. Santana,  H. Karshenas, C. Bielza, and P. Larrañaga. Regularized k-order Markov Models in EDAs. In Companion Proceedings of the 2011 Genetic and Evolutionary Conference (GECCO-2011), Dublin, Ireland. ACM Digital Library. Pp. 593-600.  2011.   

R. Santana,  C. Bielza, and P. Larrañaga. Affinity Propagation Enhanced by Estimation of Distribution Algorithms. In Proceedings of the 2011 Genetic and Evolutionary Conference (GECCO-2011), Dublin, Ireland. ACM Digital Library.  Pp. 331-338. 2011.  

R. Santana,  H. Karshenas, C. Bielza, and P. Larrañaga. Quantitative Genetics in Multi-Objective Optimization Algorithms: From Useful Insights to Effective Methods. In  Proceedings of the 2011 Genetic and Evolutionary Conference (GECCO-2011), Dublin, Ireland. ACM Digital Library.  Pp. 91-92.  2011.    

A. LaTorre, S. Muelas, J. M. Pena, R. Santana, A. Merchan-Perez and J. R. Rodriguez Differential evolution algorithm for the detection of synaptic vesicles. In Proceedings of the of the 2011 Congress on Evolutionary Computation (CEC-2011), New Orleans, U.S. IEEE Press. Pp. 1687-1694. 2011.

C. Echegoyen, Q. Zhang, A. Mendiburu, R. Santana, and J. A. Lozano. On the limits of effectiveness in estimation of distribution algorithms. In Proceedings of the of the 2011 Congress on Evolutionary Computation (CEC-2011), New Orleans, U.S. IEEE Press.Pp. 1573-1580.   2011.

H. Karshenas, R. Santana, C. Bielza and P. Larrañaga. Multi-objective optimization with joint  probabilistic modeling of objectives and variables. In Proceedings of the Evolutionary Multi-objective Optimization Conference (EMO-2011). Lecture Notes in Computer Science. Springer-Verlag, Brazil.  Pp. 298-312. 2011.
 
C. Echegoyen, Q. Zhang, A. Mendiburu, R. Santana, and J. A. Lozano.  Analyzing limits of effectiveness in different implementations of estimation of distribution algorithms.  Technical Report EHU-KZAA-TR-2/2011, Department of Computer Science and Artificial Intelligence, University of the Basque Country, January 2011.
 
H. Karshenas, R. Santana, C. Bielza and P. Larrañaga. Regularized model learning in estimation of distribution algorithms for continuous optimization problems. Technical Report UPM-FI/DIA/2011-1, Department of  Artificial Intelligence, Faculty of Informatics, Technical University of  Madrid. January, 2011. 
 




2010

R. Santana, A. Mendiburu, N. Zaitlen, E. Eskin and J. A. Lozano. Multi-marker tagging SNP selection using estimation of distribution algorithms. Artificial Intelligence in Medicine.  Vol. 5 No. 3. Pp. 193-201. 2010.
 

H. Karshenas, R. Santana, C. Bielza, and P. Larrañaga. Multi-Objective Decomposition with Gaussian Bayesian Networks. In International Conference on Metaheuristics and Nature Inspired Computing META-2010, Djerba, Tunisia.  Accepted for presentation. 2010.

R. Santana, C. Bielza and P. Larrañaga. Network measures for re-using problem information in EDAs. Technical Report UPM-FI/DIA/2010-3, Department of  Artificial Intelligence, Faculty of Informatics, Technical University of  Madrid. June, 2010.

C. Echegoyen, A. Mendiburu, R. Santana, and J.A. Lozano. Estimation of Bayesian networks algorithms in a class of complex networks. In Proceedings of the of the 2010 Congress on Evolutionary Computation (CEC-2010), Barcelone, Spain. IEEE Press.  2010.

A. Cuesta-Infante, R. Santana, C. Bielza, and P. Larrañaga, and J. I. Hidalgo. Bivariate empirical and n-variate Archimedean copulas in estimation of distribution algorithms. In Proceedings of the of the 2010 Congress on Evolutionary Computation (CEC-2010), Barcelone, Spain. IEEE Press.
 
R. Santana, C. Bielza, and P. Larrañaga. Classification of MEG data using a combined machine learning approach. Accepted for presentation at the  Workshop Data analysis competition: Connectivity and multivariate classification approaches of the 17th International Conference of Biogmagnetism. Dubrovnik, Croacia.  2010.
 
R. Santana, C. Bielza, and P. Larrañaga. Synergies between network-based representation and probabilistic graphical models for classification, inference and optimization problems in neurosciences. In Proceedings of the Twenty Third International Conference on Industrial, Engineering & Other Applications of Applied Intelligent Systems (IEA-AIE 2010). Lecture Notes in Computer Science. Springer-Verlag, Cordoba-Spain. Accepted for publication. 2010.

R. Santana, C. Bielza, and P. Larrañaga. Using probabilistic dependencies improves the search of conductance-based compartmental neuron models. In Proceedings of the Seventh European Conference on Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics (EVO-BIO). Lecture Notes in Computer Science. Springer-Verlag Istambul-Turkey. Accepted for publication. 2010.

R. Santana, C. Bielza, P. Larrañaga, J. A. Lozano,  C. Echegoyen, A. Mendiburu,   R. Armañanzas, and S. Shakya. Mateda2.0: Estimation of distribution algorithms in MATLAB Journal of Statistical Software.  Vol. 35 No. 7 Pp. 1-30. 2010.
 
C. Echegoyen, A. Mendiburu, R. Santana, and J. A. Lozano. Analyzing the k Most Probable Solutions in EDAs based on Bayesian NetworksIn Exploitation of linkage learning in evolutionary algorithms. Evolutionary Learning and Optimization. Springer. Y.-P. Chen editor.
 
R. Santana, P. Larrañaga, and J. A. Lozano. Learning factorizations in estimation of distribution algorithms using affinity propagation.   Evolutionary Computation. Vol. 18. No. 4. Pp. 515-546. 2010




2009


C. Echegoyen, A. Mendiburu, R. Santana, J.A. Lozano. A quantitative analysis of estimation of distribution algorithms based on Bayesian networks. Technical Report EHU-KZAA-TR-2-2009, Department of Computer Science and Artificial Intelligence, University of the Basque Country, September 2009.

R. Santana, A. Mendiburu, N. Zaitlen, E. Eskin, and J. A. Lozano. On the application of estimation of distribution algorithms to multi-marker tagging SNP selection. Technical Report EHU-KZAA-IK-4/09, Department of Computer Science and Artificial Intelligence, University of the Basque Country, July 2009.

R. Santana, P. Larrañaga, and J. A. Lozano. Learning factorizations in estimation of distribution algorithms using affinity propagation.   Evolutionary Computation. Accepted for publication. 

R. Santana,  C. Bielza, J. A. Lozano, and P. Larrañaga. Mining probabilistic models learned by EDAs in the optimization of multi-objective problems.  In Proceedings of the 2009 Genetic and Evolutionary Conference (GECCO-2009) , Montreal, Canada. ACM Digital Library.  2009. Pp. 445-452.  

R. Santana, C. Echegoyen, A. Mendiburu, C. Bielza, J. A. Lozano, P. Larrañaga, R. Armañanzas and S. Shakya. MATEDA: A suite of EDA programs in Matlab. Technical Report EHU-KZAA-IK-2/09, Department of Computer Science and Artificial Intelligence, University of the Basque Country, February 2009. MATEDA code is available here.

C. Echegoyen, A. Mendiburu, R. Santana, and J. A. Lozano. Analyzing the probability of the optimum in EDAs based on Bayesian networks. In Proceedings of the 2009 Congress on Evolutionary Computation (CEC-2009), Norway, 2009. IEEE Press. Pp. 1652-1659.

C. Echegoyen, A. Mendiburu, R. Santana, and J. A. Lozano. Estudio de la probabilidad del optimo en EDAs basados en redes Bayesianas. In Proceedings of the VI Congreso Español sobre Metaheurísticas, Algoritmos Evolutivos y Bioinspirados (MAEB-2009), Malaga, Spain, 2009.

R. Santana, P. Larrañaga, and J. A. Lozano. Research topics in discrete estimation of distribution algorithms.   Memetic Computing. Vol 1. No. 1. Pp. 35-54. 



2008



S. Shakya and R. Santana. A Markovianity based Optimisation Algorithm. Technical Report EHU-KZAA-IK-3/08, Department of Computer Science and Artificial Intelligence, University of the Basque Country, September 2008.

R. Armañanzas, I. Inza, R. Santana, Y. Saeys, J. L. Flores, J. A. Lozano, Y. Van de Peer, R. Blanco, V. Robles, C. Bielza and P. Larrañaga. A review of estimation of distribution algorithms in bioinformatics.   BioData Mining. 1:6.  

R. Santana, P. Larrañaga, and Jose A. Lozano. Adding probabilistic dependencies to the search of protein side chain configurations using EDAs. In Proceedings of the 10th International Conference on Parallel Problem Solving From Nature (PPSM-2008). . Dortmund, Germany.   2008. Pp. 1120-1129.  

R. Santana, A. Mendiburu and Jose A. Lozano. An empirical analysis of loopy belief propagation in three topologies: grids, small-world networks and random graphs. In Proceedings of the Fourth European Workshop on Probabilistic Graphical Models (PGM-2008). Hirtshals, Denmark.   2008. Pp. 249-256.  

S. Shakya and R. Santana. An EDA based on local Markov property and Gibbs sampling. In Proceedings of the 2008 Genetic and Evolutionary Conference (GECCO-2008), Atlanta, US. ACM Digital Library.  2008. Pp. 475-476.  

C. Echegoyen, R. Santana, J. A. Lozano, and P. Larrañaga. The impact of probabilistic learning algorithms in EDAs based on Bayesian networks.   In Linkage in Evolutionary Algorithms. Studies in Computational Intelligence Series. Springer. Y.-P. Chen and M.-H. Lim editors. Pp. 109-139.   2008.

R. Santana, P. Larrañaga and J. A. Lozano. Component weighting functions for adaptive search with EDAs. In Proceedings of the 2008 Congress on Evolutionary Computation (CEC-2008), Hong Kong, 2008. IEEE Press. Pp 4067-4074.

R. Santana, P. Larrañaga, and J. A. Lozano. Protein folding in simplified models with  estimation of distribution algorithms.   IEEE Transactions on Evolutionary Computation. Vol. 12. No. 4. Pp. 418-438. 

R. Santana, J. A. Lozano, and P. Larrañaga. Adaptive estimation of distribution algorithms.   In Adaptive Metaheuristics. Studies in Computational Intelligence Series. Springer. C. Cotta, M. Sevaux and K. Soerensen editors. Pp. 177-197. 

R. Santana, P. Larrañaga, and J. A. Lozano. Learning factorizations in estimation of distribution algorithms using affinity propagation. Technical Report EHU-KZAA-IK-1/08, Department of Computer Science and Artificial Intelligence, University of the Basque Country, January 2008.

R. Santana, J. A. Lozano and P. Larrañaga. Combining variable neighborhood search and estimation of distribution algorithms in the protein side chain placement problem. Journal of Heuristics. Vol. 14. Pp 519-547.  



2007


R. Hoens, R. Santana, P. Larrañaga, and J. A. Lozano. Optimization by Max-Propagation Using Kikuchi Approximations. Technical Report EHU-KZAA-IK-2/07, Department of Computer Science and Artificial Intelligence, University of the Basque Country, November 2007.

A. Mendiburu, R. Santana, and J. A. Lozano. Introducing Belief Propagation in Estimation of Distribution Algorithms: A Parallel Approach. Technical Report EHU-KAT-IK-11-07, Department of Computer Science and Artificial Intelligence, University of the Basque Country, October 2007.

R. Santana, P. Larrañaga, and J. A. Lozano. Challenges and open problems in discrete EDAs. Technical Report EHU-KZAA-IK-1/07, Department of Computer Science and Artificial Intelligence, University of the Basque Country, October 2007.

C. Echegoyen, R. Santana, J. A. Lozano, and P. Larrañaga. Aprendizaje exacto de redes Bayesianas en algoritmos de estimación de distribuciones. In Memorias de las Jornadas de Algoritmos Evolutivos y Metaheurísticas (JAEM I).  Zaragoza, 2007. Pp. 277-284.

C. Echegoyen, J. A. Lozano, R. Santana,  and P. Larrañaga. Exact Bayesian network learning in estimation of distribution algorithms. In Proceedings of the 2007 Congress on Evolutionary Computation (CEC-2007), Singapore, 2007. IEEE Press. Pp. 1051-1058.

A. Mendiburu,  R. Santana,  J. A. Lozano, and E. Bengoetxea. A parallel framework for  loopy belief propagation.  In Workshops Proceedings of the 2007 Genetic and Evolutionary Conference (GECCO-2007), London, UK. ACM Digital Library.  2007. Pp. 2843-2850.  


R. Santana, J. A. Lozano and P. Larrañaga. The role of a priori information in the minimization of  contact potentials by means of estimation of distribution algorithms.   Proceedings of the Fifth European Conference on Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics. Lecture Notes in Computer Science. Valencia,  2007. Pp. 247-257.

R. Santana, J. A. Lozano and P. Larrañaga.  Algoritmos de Estimación de Distribuciones para el problema de la determinación de la cadena lateral de una proteína.  Memorias del V Congreso Español de Algoritmos Evolutivos y Bioinspirados.  Tenerife, 2007. Pp. 663-670.

R. Santana, P. Larrañaga, and J. A. Lozano. Side chain placement using estimation of distribution algorithms. Artificial Intelligence in Medicine. 39(1). 2007. Pp. 49-63.


2006


P. Larrañaga, B. Calvo, R. Santana, C. Bielza, J. Galdiano, I. Inza, J. A. Lozano, R. Armañanzas, G. Santafé, A. Pérez and V. Robles. Machine learning in Bioinformatics. Briefings in Bioinformatics. 7. 2006. Pp. 86-112. [bib]

R. Santana, P. Larrañaga, and J. A. Lozano. Mixtures of Kikuchi approximations. Proceedings of the 17th European Conference on Machine Learning ( ECML-2006). Lecture Notes in Artificial Intelligence. Berlin, Germany. 2006. Pp. 365-376

2005
R. Santana. Estimation of distribution algorithms with Kikuchi approximations. Evolutionary Computation, 13(1):67-97, 2005.[ link ]

Y. M. Alvarez-Ginarte, R. Crespo, L. A. Montero-Cabrera, J. A. Ruiz-García, Y. M. Ponce, R. Santana, E. Pardillo-Fontdevila, and E. Alonso-Becerra. A novel in-silico approach for QSAR studies of anabolic and androgenic activities in the 17-hydroxy-5-androstane steroid family. QSAR & Combinatorial Science, 4:218-226, 2005.[ link ]

R. Santana, P. Larrañaga, and J. A. Lozano. Interactions and dependencies in Estimation of Distribution Agorithms. In Proceedings of the 2005 Congress on Evolutionary Computation (CEC-2005), Edinburgh, U.K., 2005. IEEE Press. Pp. 1418-1425.[ bib ]

R. Santana, P. Larrañaga, and J. A. Lozano. Aprendizaje y muestreo de la aproximación Kikuchi. In Proceedings of the III Taller Nacional de Minería de Datos y Aprendizaje (TAMIDA-2005), Granada, Spain, 2005. Thomson. Pp. 97-105.[ bib ]

R. Santana, P. Larrañaga, and J. A. Lozano. Protein structure prediction in simplified models with estimation of distribution algorithms. In Proceedings of the IV Congreso Español sobre Metaheurísticas, Algoritmos Evolutivos y Bioinspirados (MAEB-2005), Granada, Spain, 2005. Thomson. Pp. 245-252.[ bib ]

R. Santana, P. Larrañaga, and J. A. Lozano. Properties of Kikuchi approximations constructed from clique based decompositions. Technical Report EHU-KZAA-IK-2/05, Department of Computer Science and Artificial Intelligence, University of the Basque Country, April 2005.
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Software